Anti-Caveolin 1 antibodies are used for the immunodetection of the protein encoded by the CAV1 gene. In humans, the canonical protein has a reported length of 178 amino acid residues and a mass of 20.5 kDa. Its subcellular localization is in the Golgi and cell membrane. A member of the Caveolin protein family, it is believed to act as a scaffolding protein within caveolar membranes. Post-translational modifications have been described, including ubiquitination, acetylation and phosphorylation. The caveolin 1 marker can be used to characterize Deep-Layer Corticothalamic And 6B Neurons, Blood Vessel Endothelial Cells, Lymphatic Vessel Endothelial Cells, and Subcapsular Sinus Ceiling Lymphatic Endothelial Cells.* Other names for this target antigen include CGL3, LCCNS, MSTP085, PPH3, VIP21, caveolin 1, caveolae protein, 22kDa, cell growth-inhibiting protein 32, and BSCL3. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4